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DetoxiGenomic Profile

DetoxiGenomic Profile

DetoxiGenomic Profile evaluates single nucleotide polymorphisms (SNPs) associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions.

What is being measured

Phase I is the first line of defense in the detoxification of all environmental toxins, including pesticides, herbicides, pollutants, and solvents, pharmaceuticals and nutraceuticals, as well as many of the body’s own waste products (including steroid hormones).

  • CYP1A1
  • CYP2A6
  • CYP2C19
  • CYP1B1
  • CYP2D6
  • CYP2C9
  • CYP3A4

Phase II is the conjugation of toxins and their elimination.

  • COMT (catechol-O-methyltransferase)
  • NAT1 (N-acetyl transferase 1)
  • NAT2 (N-acetyl transferase 2)
  • GSTM1 (glutathione s-transferase M, isoforum)
  • GSTP1 (glutathione s-transferase P, isoforum)
  • GSTT1 (glutathione s-transferase)
  • SOD1 (superoxide dismutase-1)
  • SOD2 (superoxide dismutase-2)

Age range this test is suitable for

Adults and children of any age.

Specimen Requirements


You will need to send your sample back to the lab via a next day postal service – If you are in the UK, Royal mail offer a suitable next day service. If you are outside of the UK then please check with your postal service for options. The cost of the test does not cover the return postage.
Please note that samples should only be posted on Monday – Thursday so that they do not arrive over the weekend when the lab is closed.
A courier returns option is offered by the lab and details will be included in with your test kit. This is an optional service and the cost is not included in with the test fee. Details about payment, should you wish to take up this offer, are included with the courier details.

Before taking this test

The buccal swab is designed to collect some loose cells in your mouth. Brush your teeth the night before the test. Do not eat any food after you have brushed your teeth. Upon awakening for the day of collection, do not brush your teeth, eat or drink anything prior to the sample collection.

See instructions inside test kit for details

Turn Around Time

26 days


All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients, is completely incidental.

Smart Nutrition DetoxiGenomic Sample Report