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NeuroGenomic Profile

NeuroGenomic Profile

The test uncovers potential genetic susceptibility to:

  • Neurodegenerative Disorders
  • Developmental Issues
  • Mood Disorders
  • Oxidative Stress
  • Detoxification Capacity

What is being measured


  • MTHFR (methylenetetrahydrofolate reductase)
  • COMT (catechol-O-methyltransferase)

These genes affect how homocysteine and methionine are metabolized to support formation of S-adenosylmethionine (SAMe). The ability to donate methyl groups affects neurologic function and is modifiable by proper B-vitamin intake.


  • GSTM (glutathione-s-transferase, M, isoforum)
  • GSTP (glutathione-s-transferase, P, isoforum)

These genes are responsible for detoxifying products of oxidative stress and carcinogens. Variants decrease detoxification capacity.

Oxidative Protection

  • SOD-2 (Superoxide dismutase -2)

These genetic variants alter anti-oxidant enzyme activity and modify requirements for anti-oxidants.

Age range this test is suitable for

Adults and children of any age

Specimen Requirements


You will need to send your sample back to the lab via a next day postal service – If you are in the UK, Royal mail offer a suitable next day service. If you are outside of the UK then please check with your postal service for options. The cost of the test does not cover the return postage.
Please note that samples should only be posted on Monday – Thursday so that they do not arrive over the weekend when the lab is closed.
A courier returns option is offered by the lab and details will be included in with your test kit. This is an optional service and the cost is not included in with the test fee. Details about payment, should you wish to take up this offer, are included with the courier details.

Before taking this test

The buccal swab is designed to collect some loose cells in your mouth. Brush your teeth the night before the test. Do not eat any food after you have brushed your teeth. Upon awakening for the day of collection, do not brush your teeth, eat or drink anything prior to the sample collection.

See instructions inside test kit for details

Turn Around Time

26 days

All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients, is completely incidental.

Smart Nutrition NeuroGenomic Sample Report