Insulin resistance/insensitivity is closely linked with obesity, and occurs when the body stops being responsive to insulin. This leads to higher and higher levels of insulin being secreted by the pancreas in an attempt to maintain normal blood sugar levels.
An association between certain metabolic disorders and cardiovascular disease has been known since the 1940s. In the 1980s this association became more clearly defined and the term Metabolic Syndrome (also known as Syndrome X, dysmetabolic syndrome or Insulin Resistance) was coined to designate a cluster of metabolic risk factors that come together in a single individual.
Metabolic syndrome is thought to affect approximately 20-30% of the population in industrialised countries.
It is a condition that can pave the way to both diabetes and heart disease, two of the most common and important chronic diseases today. Metabolic syndrome increases the risk of type 2 diabetes anywhere from 9-30 times over the normal population, and the risk of cardiovascular disease from 2-4 times that of the normal population. Other problems that stem from metabolic syndrome include fatty liver, kidney damage, obstructive sleep apnoea, polycystic ovary syndrome, increased risk of dementia with aging, and cognitive decline in the elderly.
As is true with many medical conditions, genetics and the environment play important roles in the development of metabolic syndrome. Environmental issues such as low activity levels, sedentary lifestyle, and progressive weight gain also contribute significantly to the risk of developing metabolic syndrome. It is present in about 5% of people with normal body weight, 22% of those who are overweight and 60% of those considered obese. Adults who continue to gain 5 or more pounds per year raise their risk of developing metabolic syndrome by up to 45%.
What is being measured
- LDL cholesterol
- HDL cholesterol
- VLDL cholesterol
- total cholesterol
- total cholesterol/HDL
- Fasting insulin
- Glycosolated Haemoglobin HbA1C
- HS C- reactive protein – HS-CRP
Type of Test
Blood test that requires a blood sample.
You will need to arrange for a blood sample to be collected by a nurse at your G.P. service or at a private clinic or hospital. Any fee for this service is not included in with the test fee.
You will need to send your sample back to the lab via a next day postal service – If you are in the UK, Royal mail offer a suitable next day service. If you are outside of the UK then please check with your postal service for options. The cost of the test does not cover the return postage.
Please note that samples should only be posted on Monday – Thursday so that they do not arrive over the weekend when the lab is closed.
A courier returns option is offered by the lab and details will be included in with your test kit. This is an optional service and the cost is not included in with the test fee. Details about payment, should you wish to take up this offer, are included with the courier details.
Before Taking this Test
Fast overnight (at least 8 hours)
Inform practitioner about medication and supplement use, including aspirin and cholesterol lowering drugs
See instructions inside test kit for details
All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients, is completely incidental.