The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of overall health. The OAT test covers intestinal yeast, fungal and bacterial levels, oxalate levels, Neurotransmitter levels, detoxification markers, vitamin requirements and mineral metabolism. Importantly the OAT test also includes mitochondrial markers – associated with the Krebbs cycle and energy production (our ability to turn protein, fat and carbohydrate into energy).
Defects of mitochondrial metabolism are associated with a wide spectrum of illness and disease. This test can reveal metabolic distress that can arise from many causes, including:
- Toxic exposure
- Nutrient deficiency
- Intestinal dysbiosis
- Oxidative stress
- Poor diet
The OAT is particularly relevant for the chronically “unwell” patient who may be experiencing
- Multiple chemical sensitivities
- Chronic fatigue syndrome
- Hypotonia (loss of muscle tone)
- pH imbalances
- Low exercise tolerance
- Muscle/joint pain
What are organic acids
Organic acids are metabolic intermediates produced in the pathways of many metabolic functions. So if a chemical in the body has to get from A to B – there are usually many steps and the organic acids are produced during these steps.
The accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. An organic acids urine test helps reveal activity and changes at the metabolic level.
What is being measured
75 organic acids
HPHPA (Clostridia marker)
4-Cresol (C. diffcile)
DHPPA (beneficial bacteria)
Glyceric • Glycolic
Homovanillic Acid (HVA)
Vanillmandelic Acid (VMA)
Quinolinic / 5-HIAA Ratio
Uracil • Thymine
Methylmalonic (Vitamin B12)
Pyridoxic (Vitamin B6)
Pantothenic (Vitamin B5)
Glutaric (Vitamin B2-Ribo avin)
Ascorbic (Vitamin C)
3-Hydroxy-3-methylglutaric (Vitamin Q10-CoQ10)
N-Acetylcysteine (Glutathione precursor and chelating agent) Methylcitric (Vitamin H-Biotin)
Age range this test is suitable for
Adults and children 2 years and above. Children must be potty trained as the sample must not have any trace of nappy fibres or stools.
Type of test
Before Taking this Test
Patients should avoid apples, grapes (including raisins), pears, cranberries and their juices 48 hours prior to specimen collection.
Avoid arabinogalactan, echinacea, reishi mushrooms, and ribose supplements for 48 hours before collection.
Women should not collect urine during their period
See instructions inside test kit for details