Methylation – The best kept optimal health secret according to Gary Brecka.

The Methylation DNA – test, popularised by Gary Brecka, offers a comprehensive analysis of genetic factors influencing the methylation process.

Methylation, which is a vital biological mechanism, governs how the body processes essential nutrients like vitamins, amino acids, and minerals. Understanding one’s methylation profile can unveil potential deficiencies or inefficiencies in nutrient processing, offering valuable insights for personalised supplementation and dietary planning.

We are big fans of Gary Brecka but if you don’t live in the US you can’t order his test. Luckily we offer a great alternative to the Gary Brecka 10X methylation test.

Gary Brecka’s 10X test covers the main 5 methylation genes.

MTHFR,  MTR, MTRR, AHCY and COMT

Our test covers everything in the 10X test plus an additional 22 genes making it the most comprehensive genetic methylation test in the UK today.

We look at;

Folate Cycle: DHFR, FOLH1, MTHFD1, MTHFR, RFC1, SHMT1 and TYMS
Methionine Cycle: AHCY, BHMT, CHDH, FUT2, MAT1A, MTR, MTRR, PEMT and TCN2
Neurotransmitter Cycle: COMT, MAOA, MAOB, MTHFR, PNMT, QDPR and VDR
Transsulphuration Cycle: CBS, CTH, GSS, MUT and SUOX
Urea Cycle: BDKRB2, NOS and SOD

Your results come with an easy to understand report with the option to upgrade and work with our team of nutritional therapists and functional medicine practitioners who are experienced in interpreting Nutritional and genetic test results.

Read more about the Genetic Methylation Test here.

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US Custom changes Aug 29 2025

Every US shipment, regardless of value or content, must now undergo full entry with U.S. Customs and Border Protection (CBP).

Our lab partners are working hard to reduce the impact of these new customs procedures on returning US bound test samples.

Unfortunately this change may impact your test results turnaround time

  • Transit times may be longer due to increased customs processing.

  • Samples may be delayed or held while clearance is completed.

If you have already sent back your sample and it is directly affected by these customs delays, our team will contact you individually to advise on the next steps.

We know how vital timely testing is for you and we greatly value your understanding while these changes take effect.

We expect the situation to improve as customs processes adjust, and we will provide updates as this develops.

Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.

The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.