Genetic Nutrient Core Requirements Test

Test your Nutrient Requirement Genes and support any areas that are compromised.

Genetic Nutrient Core Requirements Test

Test your Nutrient Requirement Genes and support any areas that are compromised.

What are Genetic Nutrient Core Requirements ?

DNA testing means we can all personalise our diet and lifestyle in a proactive way for optimal health and wellbeing.

Nutrient Core provides insights into the essential genetic interactions with diet and lifestyle, identifying if certain functions need additional genetic testing. It covers genes that impact the following:

  • Appetite control and blood sugar balance, looking at the hormones, leptin and insulin
  • Vitamins and minerals requirements and how you convert these in the body. This covers vitamin A, C, D and K and the B vitamins B9 (folate) and B12 (cobalamin)
  • Detoxification capabilities
  • Food intolerance – this covers gluten and lactose that have genetic susceptibility
  • Caffeine – how sensitive you are and how you metabolise this
  • Diversity of the microbiome
  • Inflammation, this includes systemic and specific in relation to infections
  • Circadian rhythm – are you genetically wired to be an early bird or night owl

Why is Genetic Susceptibility for Nutrients Important?

The importance of this test is really so that you can be proactive for your health. Potentially uncovering information that can prevent future health problems or get to the bottom of symptoms that you currently have.

What does the Genetic Nutrient Requirements Test do?

The Genetic Nutrient Requirements Test looks at your DNA to find tiny differences called SNPs, which can affect your health and how your body works. These differences can influence things like how your body processes nutrients, metabolises food and how responds to certain foods. Understanding them helps you make better choices for your health.

The Genetic Nutrient Requirement Test reveals whether an individual might struggle with or excel in processing cofactors such as folate, vitamin B12 and other vitamins including vitamin A, C, D and K. It also looks at your food response to lactose, gluten, caffeine and salt sensitive hypertension. It gives us information on your microbiome diversity that often underpins many health conditions, in addition to looking at some key detoxification markers and glutathione.

How we metabolise foods and the hormones that impact these, such as leptin and insulin, will have a big impact on our weight and appetite control. Inflammatory markers are covered, with these often-underpinning infection and immunity. Finally, you can find out what your genetic predisposition is regarding circadian rhythm, are you a night owl or early bird.

Who would benefit most from the Genetic Nutrient Requirement Test?

An imbalance in how the body absorbs certain nutrients, metabolises foods and how it responds to certain foods such as gluten, dairy and caffeine effects our susceptibility to various health conditions. This would be individual specific and is not an exhaustive list but these could include:

  • Obesity – looking at genes involved in appetite control, especially leptin as this we can develop leptin resistance, which causes appetite or hunger to not be switched off. The nutrient requirement test also looks at the FTO gene and your bodies predisposition towards obesity.
  • Vitamin A deficiency can result in poor night vision, poor immunity and also increased risk of thyroid and skin conditions
  • Folate and Vitamin B12 are essential components of the methylation cycle and this test looks at how this is converted and absorbed in the body. Deficiencies in this area can be linked with neurological conditions, developmental disorders, cardiovascular disease, chronic fatigue and oxidative stress.
  • Premature ageing – importance of vitamin C and collagen
  • Poor immunity – this would be influenced by vitamin C gene and some of the detoxication genes
  • Osteoporosis and other musculoskeletal degenerative disorders – the collagen gene can influence disease progression in these areas.

 

What is being measured in the Genetic Nutrient Requirement Test?

The genetic Nutrient Requirement Test assesses genes associated with the below:

Food Response: HLA-DQA1, HLA-DQB1 and LCT
Caffeine: CYP1A2 and ADORA2A
Microbiome: FUT2
Vitamins: BCO1, MTHFR, FUT2, TCN2, SLC23A1, COL1A1, GC, VDR and VKORC1
Blood Pressure: ACE and AGT
Detoxification: GSTM1
Metabolism: FADS1/2, FTO, TCF7L2, PGC1A and LEPR
Inflammation: TNF and IFNG
Circadian Rhythm: CLOCK and PER1

What will I get with the Genetic Nutrient Requirement Test results?

  1. Clearly illustrated and customized, color-coded genotype information.
  2. Descriptions elaborating on your gene functionality and the effects of SNP (Single Nucleotide Polymorphism).
  3. Clinically significant SNPs.
  4. Insights into nutrient and other epigenetic influences.
  5. A fully referenced report with links to research evidence.

What if I need help with the results of the Genetic Nutrient Requirement Test results?

We have a team of functional medicine practitioners and registered nutritional therapists that we can refer you to help you with your results should you need any additional support. This is not included in the cost of the test.

What happens to my DNA after the Genetic Nutrient Requirement Test?

Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction at 5 months and completely destroyed by 6 months.

The client report, the data and the DNA sample is never (and will never be) shared with, or sold to third parties. All of the data extraction and analysis is done in the UK.

At Smart Nutrition we pride ourselves in offering the best cost possible for the Genetic Nutrient Requirement test.

 

Defects in nutrient requirements are wide and varied and have been associated with many clinical conditions including, but not limited to:

Obesity

Poor immunity

Poor night vision

Cardiovascular disease

Neurological conditions

Premature ageing

Osteoporosis

Neurodegenerative conditions including Alzheimer’s Disease

 

The genetic Nutrient Requirement Test assesses genes associated with the below:

Food Response: HLA-DQA1, HLA-DQB1 and LCT
Caffeine: CYP1A2 and ADORA2A
Microbiome: FUT2
Vitamins: BCO1, MTHFR, FUT2, TCN2, SLC23A1, COL1A1, GC, VDR and VKORC1
Blood Pressure: ACE and AGT
Detoxification: GSTM1
Metabolism: FADS1/2, FTO, TCF7L2, PGC1A and LEPR
Inflammation: TNF and IFNG
Circadian Rhythm: CLOCK and PER1

Buccal cheek swab.

Collecting your samples for the genetic Nutrient Requirement test is simple, it is a non invasive cheek swab and is suitable for all ages as long as a cheek swab can be collected.

You need to have a break from eating and drinking at least one hour before doing the genetic nutrient requirement test.

The genetic nutrient requirement test is available for anyone, including children, with the consent of a parent or guardian. When testing a child under 18, parental consent is required.

UK Orders

All UK orders for the genetic nutrient requirement test include return packaging and postage for return within the UK. The package can be put in a standard post box.
It can also be sent tracked or special delivery via a post office, the fee for this is not included.

Non UK Orders

The DNA test kit is declared as a value of £4 for customs purposes. The package may be subject to customs/ import duties, for which the recipient is liable and responsible to settle.
If kits are returned due to you not accepting fees or delivery, we are sorry but the order is not refundable.International orders return packaging is provided but it is NOT prepaid. You will need to arrange and pay for the return. For returns from Europe we recommend a tracked postal service. As samples are stable it is not necessary to choose an express service.
For Non UK orders please contact [email protected] if your country is not available at the checkout.

Results for the genetic nutrient requirement test are available in 2.5 weeks.

Your genetic nutrient requirement test results will be emailed to you.

We are here to offer ongoing support as you progress through your health journey, regardless of your test results. Should you have any inquiries or require additional assistance we are happy to help you.

Your next steps

If you feel you need additional support in addressing your health concerns, we suggest considering collaboration with the Functional Medicine and Nutrition Consultations Clinic. (website coming soon)

Renowned for their expertise, the Functional Medicine and Nutrition Consultations Clinic comprises a team of experienced nutritional therapists and certified functional medicine practitioners who excel in addressing complex health issues.Working with genetic test results needs specialised training. Chosen carefully both Olga Hamilton and Karen Preece Smith have completed their nutrigenomics training and are ready to help you.

More information about the team of qualified functional medicine and registered Nutritional therapy practitioners that are ready to help you.

Karen Preece Smith 

Methylation and Nutrition Function Medicine:
Karen has worked with nutrigenomics since 2019. She has undertaken further training with leading UK genetic lab, Lifecode Gx, to become one of their recognised Nutrigenomic practitioners. She understands Nutrient Requirements genes well and can simplify their findings in relation to your CFS, digestive or hormonal issues as well as those issues which affect mental health and neurodiversity.
Olga Hamilton
Olga has been using DNA/genetics testing in her practice since 2015 to help her build personalised wellbeing and anti-ageing programmes. Genetic testing tells us how and where you are different from all other people, not just disease risks and predispositions, but also helps us tailor your diet and micronutrients. It is extremely helpful in personalising your diet and helps in prevention of genetic disorders.

As you can see Olga and Karen can help you address areas highlighted by your genetic nutrient requirements test results, crafting a personalised plan tailored to your specific needs. This comprehensive approach would include recommendations regarding your Genetic Nutrient Requirement test results and any necessary further diagnostic testing depending on your goals, supplementation, dietary adjustments, and lifestyle recommendations, all presented with clear, easy-to-follow guidance.

How to Book your appointment

We will send you details of how to book with the clinic along with your results.

How much will it cost.

£150 an hour but you will also receive a £20 off your first appointment discount code with the results.

How many sessions will I need to understand my Genetic Nutrient Requirement test result

Many people book a 1 hour session to go over and understand their results.And lots of people want further ongoing support as they want to address their health concerns in more details.

Which lab do you use to process the genetic nutrient requirement test results?

We use lifecodeGX for our genetic nutrient requirement test.

 

Is the laboratory processing my genetic nutrient requirement results accredited and reputable?

Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction after 5 months and completely destroyed by 6 months.

Please see the ISO Certifications below:

  • Certification to ISO 9001 for business processes;
  • Certification to ISO 13485 for the manufacturing of substances that support health care processes and systems;
  • Accreditation to ISO 17025, for laboratory testing and calibration services;
  • Compliance with Good Laboratory Practice (GLP), Good Clinical Practice (GCP), Good Distribution Practice (GDP) and current Good Manufacturing Practice (cGMP) for pharmaceutical studies and pharmaceutical related processes;
  • Accreditation to ISO 17043 for the operation and management of proficiency testing schemes;
  • Accreditation to ISO 17034 for reference material production facilities.

Genetic Nutrient Core Requirements Test

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Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.

The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.