Cyrex Array 12 Pathogen Immune

Cyrex Array 12 Pathogen Immune

Cyrex put together this test to detect immune reaction to key pathogens that may lead to multiple autoimmune reactivities.

Many microbes are completely harmless, and some, like the microbes that live inside a healthy gut, have many benefits! A pathogen is a microbe that causes disease. These can be bacteria, fungi, viruses or parasites and when present in the body in sufficient number, can cause harm.

When a pathogen invades the human host, it can cause acute infection. Most of these acute infections manifest as gastrointestinal or flu-like symptoms such as diarrhoea, fatigue and fever. If the immune system is able to launch an appropriate response to the invading microbe it should be cleared from the body.

However, in some cases, the pathogen actually remains inside the body in a latent state. What’s more, some people acquire and carry a pathogen without ever experiencing an acute infection. The undetected pathogen may not result in symptoms for many years.

A pathogen that is hiding out inside the body’s cells, not causing acute symptoms but still releasing toxins can lead to immune dysfunction, chronic inflammation and tissue damage. This is thought to be a key factor in the development and continuation of autoimmune diseases.

The Pathogen Associated Immune Reactivity Screen identifies oral, viral, gastrointestinal, viral and tick-borne pathogens that are in a latent or chronic reactivating state and therefore contributing to inflammation and autoimmune reactivity. It also pinpoints gastrointestinal parasites, environmental fungi and bacterial and stealth pathogens, so is recommended for people who:

  • Present with an autoimmune disease that may have been exposed to bacteria, viruses, parasites or moulds. For example from a tick bite, a dental problem, past gastrointestinal disease or moulds at home or in the working environment.
  • Present with chronic conditions such as gastrointestinal distress, fatigue, body aches or unexplained and general inflammation, including neuroinflammation.
  • Have not fully responded to clinical interventions, such as detoxification and dietary modifications.
  • Streptococcus mutans
  • Porphyromonas gingivalis
  • Helicobacter pylori
  • Campylobacter jejuni
  • Yersinia enterocolitica
  • Clostridium difficile
  • Candida albicans
  • Rotavirus
  • Entamoeba histolytica
  • Giardia lamblia
  • Cryptosporidium
  • Blastocystis hominis
  • Human + chlamydia HSP-60
  • Chlamydias
  • Streptozymes
  • Streptococcal M protein
  • Mycoplasmas
  • Acinetobacter
  • Klebsiella
  • Mycobacterium avium
  • Aspergillus
  • Penicillium
  • Stachybotrys chartarum
  • Citrullinated EBV
  • Hepatitis C virus
  • Cytomegalovirus
  • Human herpesvirus-6
  • Borrelia burgdorferi
  • Babesia + Ehrlichia +Bartonella


This is a blood test that requires a blood sample which will then need to be centrifuged. Centrifuge can be carried out at the lab if the sample is received within 24 hours from the blood draw.

You will need to arrange for a blood sample to be collected either at a laboratory in London, by a nurse at your GP service or at a private clinic or hospital. Any fee for this service is not included with the test fee.


While Cyrex is unable to provide an exhaustive list of medications due to the interactive complexities and varieties of medications and patient circumstances, the following have been noted:

  • Immunosuppressant and corticosteroid drugs can reduce antibody production and cause false negative results.
  • Limited assessments on the effects of aspirin, acetaminophen, and antipsychotics on Arrays 1-4 have been performed. No noticeable effects were observed.
  • Inhalers can affect the results of Cyrex’s oral fluid testing (Array 1). Wait two weeks after completion of inhalant dosages before collecting the specimen.
  • Unknown cross-reactive epitopes from foods and microorganisms may stimulate the antibody production in the absence of a true antigen. Cyrex has already developed Array 4 in order to recognise the most common antigens in this regard.
  • A gluten-free diet can cause false negative results on gluten protein/peptide tests.
  • Certain conditions, such as ileal pouch surgery, may cause a false positive celiac serology.

Please do not stop any medication without your doctor’s consent.


3 years and above.

Once you’ve collected your sample, please send it back to the lab using the prepaid return label.

Please note that samples should only be posted on Monday – Thursday so that they do not arrive over the weekend when the lab is closed.

14-21 days.

Your test results will be emailed to you.

Cyrex Array 12 Pathogen Immune


Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.

The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.