The Metabolomix+ test evaluates the following:
Organic acids (urine)
Malabsorption and dysbiosis markers are metabolites produced by the gastrointestinal microbiome.
Cellular energy and mitochondrial markers are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle.
Vitamin markers are specific analytes used to assess functional levels of vitamin cofactors.
Neurotransmitter metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine.
Toxin and detoxification markers relate to certain toxic metabolites and the body’s detoxification capacity.
Oxalate markers relate to kidney stone formation, oxidative stress and metabolic dysfunction.
Amino acids (urine)
Essential amino acids must be derived from dietary sources.
Nonessential amino acids are synthesised by the body.
Intermediary metabolites are byproducts of amino acid metabolism.
Dietary peptide related markers can indicate incomplete protein breakdown.
Oxidative stress markers (urine)
Include the oxidative damage markers lipid peroxides and 8-OH.
Add-on essential and metabolic fatty acids (bloodspot)
Omega 3 fatty acids are essential for brain function and cardiovascular health and are anti-inflammatory.
Omega 6 fatty acids are involved in the balance of inflammation.
Omega 9 fatty acids are important for brain growth, nerve cell myelin, and reducing inflammation.
Saturated fatty acids are involved in lipoprotein metabolism and adipose tissue inflammation.
Monounsaturated fats include omega 7 fats and unhealthy trans fats.
Delta-6 desaturase activity assesses efficiency of this enzyme to metabolise omega 6s and omega 3s.
Cardiovascular risk includes specific ratios and the omega 3 index.
Add-on Nutrient and Toxic Elements (urine)
Assesses 20 toxic and 15 mineral elements.
Add-on SNPs – buccal swab
MTHFR, COMT, TNF-a, and APOE.