3 years and above. Children must not be in nappies.
The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of overall health. It also includes mitochondrial markers, which are associated with the Krebs cycle and energy production (our ability to turn protein, fat and carbohydrate into energy).
The OAT test looks at biomarkers for:
Defects of mitochondrial metabolism are associated with a wide spectrum of illness and disease. This test can reveal metabolic distress that can arise from many causes, including:
The OAT is particularly relevant for the chronically unwell patient who may be experiencing:
Organic acids are metabolic intermediates produced in the pathways of many metabolic functions. If a chemical in the body has to get from A to B, there are usually many steps. The organic acids are produced during these steps.
The accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up or drug effect. An organic acids urine test helps reveal activity and changes at the metabolic level.
Citramalic
5-Hydroxymethyl-2-furoic
3-Oxoglutaric
Furan-2,5-dicarboxylic
Furancarbonylglycine
Tartaric
Arabinose
Carboxycitric
Tricarballylic
2-Hydroxyphenylacetic
4-Hydroxyphenylacetic
4-Hydroxybenzoic
4-Hydroxyhippuric
Hippuric 3-Indoleacetic
Succinic
HPHPA (Clostridia marker)
4-Cresol (C. difficile)
DHPPA (beneficial bacteria)
Glyceric
Glycolic
Oxalic
Lactic
Pyruvic
2-Hydroxybutyric
Fumaric
Malic
2-Oxoglutaric
Aconitic
Citric
Homovanillic acid (HVA)
Vanillmandelic acid (VMA)
HVA/VMA ratio
5-Hydroxyindoleacetic (5-HIAA)
Quinolinic
Kynurenic
HVA/DOPAC ratio
Dihydroxyphenylacetic (DOPAC)
Uracil
Thymine
3-Hydroxybutyric
Acetoacetic
4-Hydroxybutyric
Ethylmalonic
Methylsuccinic
Adipic
Suberic
Sebacic
Methylmalonic (vitamin B12)
Pyridoxic (vitamin B6)
Pantothenic (vitamin B5)
Glutaric (vitamin B2-riboflavin)
Ascorbic (vitamin C)
3-Hydroxy-3-methylglutaric (vitamin Q10-CoQ10)
N-Acetylcysteine (glutathione precursor and chelating agent)
Methylcitric (vitamin H-Biotin)
Pyroglutamic
Orotic
2-Hydroxyhippuric
2-Hydroxyisovaleric
2-Oxoisovaleric
3-Methyl-2-oxovaleric
2-Hydroxyisocaproic
2-Oxoisocaproic
2-Oxo-4-methiolbutyric
Mandelic
Phenyllactic
Phenylpyruvic
Homogentisic
4-Hydroxyphenyllactic
N-Acetylaspartic
Malonic
3-Methylglutaric
3-Hydroxyglutaric
3-Methylglutaconic
Phosphoric
Urine sample.
Patients should avoid apples, grapes (including raisins), pears, cranberries and their juices 48 hours prior to specimen collection.
Avoid arabinogalactan, echinacea, reishi mushrooms, and ribose supplements for 48 hours before collection.
Women should not collect urine during their period.
Full instructions will be sent with the test kit.
3 years and above. Children must not be in nappies.
Return using the included prepaid label and shipping instructions. If the next day is not a working day in the UK, please keep your sample in the freezer to ensure that it arrives at the lab Monday-Thursday.
Your test results will be emailed to you.
All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients is completely incidental.
Updated April 2020
