The UK’s most comprehensive genetic methylation test using the Gary Brecka method. Simple home cheek swab kit — includes GP and Functional Medicine Practitioner comments with your results
The Organic Acids Test (OAT) is a powerful, non-invasive tool that provides a detailed metabolic snapshot of your overall health. By analysing urine samples for over 70 markers, this test offers valuable insights into crucial bodily functions, highlighting potential nutrient deficiencies, detoxification issues, neurotransmitter imbalances, and digestive health.
One of the standout features of the OAT is its assessment of mitochondrial markers, which are closely linked to the Krebs cycle – the body’s core energy production process. These markers help evaluate how efficiently your body converts proteins, fats, and carbohydrates into usable energy.
If you’re struggling with fatigue, mood imbalances, poor concentration, or unexplained symptoms, the OAT can help uncover metabolic imbalances at the root.
A simple do at home urine test that measure levels of organic acids in the urine that reflect how well different aspects of metabolism are working. By examining these organic acids, the OAT test can uncover a range of imbalances and inefficiencies in key bodily systems. The OAT test is useful for identifying functional deficiencies, microbial overgrowths, yeast overgrowth and mitochondrial stress.
Here’s a closer look at what the OAT measures:
Altogether, the OAT provides a comprehensive metabolic profile, making it a powerful tool for those looking to get to the root of chronic symptoms and optimise health.
The OAT can help identify hidden imbalances in your metabolism, often before they appear in standard blood work. It offers early insight into mitochondrial dysfunction, which can be linked to a wide range of health concerns, including fatigue, mood issues, and chronic illness.
This test helps uncover metabolic stress caused by:
By pinpointing the root causes of dysfunction, the OAT supports targeted, personalised health interventions.
The Organic Acids Test is particularly useful for individuals experiencing persistent, unexplained symptoms.
It may benefit those dealing with fatigue, brain fog, low mood, anxiety, poor sleep, recurrent yeast infections, or ongoing health concerns that have not been identified through standard testing
You may benefit from the OAT if you experience:
If you’re experiencing complex or long-term health issues, this test can help to uncover hidden biochemical imbalances that may be driving symptoms and guide more effective, personalised treatment plans.
To ensure accurate results, please follow these guidelines:
Can the Organic Acids Test Detect Candida and Yeast Overgrowth?
The OAT includes a dedicated fungal marker panel that can identify elevated yeast metabolites in the gut. Markers such as arabinose, citramalic, and tartaric acid — when elevated — may indicate Candida or yeast overgrowth. This is one of the most clinically valuable aspects of the test for those with chronic digestive symptoms, fatigue, brain fog, or recurrent yeast infections. Your results will include a comment from both a GMC-registered GP and a Functional Medicine Practitioner explaining what any elevated fungal markers may mean for you.
Take the first steps towards better health. The Organic Acids Test offers a powerful window into your body’s metabolic function, helping you make informed, personalised decisions to support your wellbeing.
Order your Organic Acids Test (Mosaic Diagnostics, formerly great plains laboratory) test today and start your journey to clearer answers and targeted solutions.
If your child is over 3 years old and still in nappies please contact us prior to ordering so that we can request a nappy collection pack for you. If this is requested after your order has been processed then an additional charge will be made.
Yes. The Organic Acids Test uses gas chromatography-mass spectrometry (GC-MS), an established and highly accurate laboratory technique, to measure metabolic byproducts in urine. It is performed by Mosaic Diagnostics (formerly The Great Plains Laboratory), which holds CLIA certification and College of American Pathologists (CAP) accreditation — two of the highest standards of laboratory quality in the world.
The OAT is widely used in functional and integrative medicine to identify metabolic imbalances that standard NHS or GP testing does not assess. It does not diagnose disease, but provides detailed biochemical data that can inform personalised health strategies.
Organic acids are chemical compounds produced as part of normal metabolism. They play a vital role in energy production, helping the body convert proteins, fats, and carbohydrates into usable fuel. They are also involved in maintaining pH balance, supporting nutrient absorption, and regulating key biochemical pathways including neurotransmitter production and detoxification.
When organic acid levels in urine are abnormal, it can indicate that one or more of these processes is not functioning optimally — which is why measuring them provides such a detailed picture of overall metabolic health.
The OAT analyses 75 organic acids in urine to reveal imbalances across multiple body systems. Markers are grouped into the following categories:
The full list of 75 markers tested includes:
Citramalic, 5-Hydroxymethyl-2-furoic, 3-Oxoglutaric, Furan-2,5-dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2-Hydroxyphenylacetic, 4-Hydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, Hippuric, 3-Indoleacetic, Succinic, HPHPA (Clostridia marker), 4-Cresol (C. difficile), DHPPA (beneficial bacteria), Glyceric, Glycolic, Oxalic, Lactic, Pyruvic, 2-Hydroxybutyric, Fumaric, Malic, 2-Oxoglutaric, Aconitic, Citric, Homovanillic acid (HVA), Vanillmandelic acid (VMA), HVA/VMA ratio, 5-Hydroxyindoleacetic (5-HIAA), Quinolinic, Kynurenic, HVA/DOPAC ratio, Dihydroxyphenylacetic (DOPAC), Uracil, Thymine, 3-Hydroxybutyric, Acetoacetic, 4-Hydroxybutyric, Ethylmalonic, Methylsuccinic, Adipic, Suberic, Sebacic, Methylmalonic (vitamin B12), Pyridoxic (vitamin B6), Pantothenic (vitamin B5), Glutaric (vitamin B2-riboflavin), Ascorbic (vitamin C), 3-Hydroxy-3-methylglutaric (CoQ10), N-Acetylcysteine (glutathione precursor and chelating agent), Methylcitric (vitamin H-Biotin), Pyroglutamic, Orotic, 2-Hydroxyhippuric, 2-Hydroxyisovaleric, 2-Oxoisovaleric, 3-Methyl-2-oxovaleric, 2-Hydroxyisocaproic, 2-Oxoisocaproic, 2-Oxo-4-methiolbutyric, Mandelic, Phenyllactic, Phenylpyruvic, Homogentisic, 4-Hydroxyphenyllactic, N-Acetylaspartic, Malonic, 3-Methylglutaric, 3-Hydroxyglutaric, 3-Methylglutaconic, Phosphoric
Yes. The OAT includes a dedicated fungal marker panel that can identify elevated yeast metabolites — including arabinose, which is a well-recognised marker associated with Candida overgrowth. Other fungal markers such as citramalic, 5-hydroxymethyl-2-furoic, tartaric, and carboxycitric acids are also measured. Elevated levels in this panel may suggest yeast or fungal dysbiosis in the gut.
Your results will include a comment from a GMC-registered GP and a Functional Medicine Practitioner to help you understand what any elevated markers may mean for you.
The OAT measures a panel of fungal metabolites that, when elevated, may indicate yeast or fungal overgrowth in the gastrointestinal tract — most commonly Candida species. Arabinose is one of the most clinically recognised of these markers and is associated with Candida activity.
If your results show elevated fungal markers, your report will include a comment from both a GMC-registered GP and a Functional Medicine Practitioner highlighting which markers are raised and what this may suggest. They will not provide a specific treatment protocol within the report, because the right course of action depends on your full health history, any medications you are taking, and other individual factors.
If you would like personalised guidance on next steps, We can refer you to Functional Medicine Practitioners who are available for consultations to help you interpret your results and create a tailored plan. You will receive a £20 discount code towards your first appointment with your results.
No. The Organic Acids Test is not designed to diagnose Small Intestinal Bacterial Overgrowth (SIBO). While the OAT does include bacterial marker panels that can indicate dysbiosis or bacterial overgrowth in the gut more broadly, a dedicated SIBO breath test is the appropriate test for diagnosing SIBO specifically.
Abnormal results on the Organic Acids Test indicate that one or more metabolic pathways may not be functioning optimally. Depending on which markers are elevated or reduced, this could reflect nutritional deficiencies, mitochondrial dysfunction, yeast or bacterial overgrowth, impaired detoxification, or neurotransmitter imbalances.
Every OAT result from Smart Nutrition includes a written comment from a GMC-registered GP and a Functional Medicine Practitioner. This comment will flag any markers of clinical significance and provide context for what they may mean.
Because abnormal results can have multiple possible causes and the appropriate response depends on your individual health history, medications, and circumstances, the report does not include a specific treatment protocol. If you would like in-depth guidance, we can refer you to practitioners that are available for follow-up consultations to help you understand your results in more detail and build a personalised plan. A £20 discount code towards your first appointment is included with every result.
Every OAT result from Smart Nutrition includes a written comment from a GMC-registered GP and a Functional Medicine Practitioner, so you receive professional clinical oversight as standard.
If you would like further support, we can refer you to experienced Functional Medicine Practitioners — Olga Hamilton and Kelly Tassi — who offer one-to-one consultations to help you interpret your results in depth and create a personalised plan covering nutrition, supplementation, and lifestyle.
No GP referral is needed. You can order the OAT directly through Smart Nutrition. Every result includes a written comment from a GMC-registered GP alongside a Functional Medicine Practitioner comment, so you receive professional clinical oversight without needing a referral.
The OAT can be taken at any age. It is suitable for both children and adults and is non-invasive, requiring only a urine sample collected at home.
A nappy collection kit will be included with the test kit for those aged up to 3 years old.
If your child is over 3 years old and still in nappies please contact us before ordering so that we can discuss the suitability of a nappy collection pack with you. If a nappy collection pack is requested after your order has been processed, an additional charge will apply.
You wil receive your results of the OAT test in 14-15 working days.
Your organic acid test results will be sent to you via email.
This sample report includes the bile acids and SCFA’s add on
All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients is completely incidental.
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£289.00
The UK’s most comprehensive genetic methylation test using the Gary Brecka method. Simple home cheek swab kit — includes GP and Functional Medicine Practitioner comments with your results
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Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.
The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.