Genetic Hormone Test

Test your Hormone Genes and support any areas that are compromised.

Genetic Hormone Test

Test your Hormone Genes and support any areas that are compromised.

What are hormones?

The body produces over 50 hormones in the body and these act as a signalling molecule that help to control and coordinate various processes including energy production, metabolism, reproduction, growth and development, response to factors such as injury, stress and the environment around us. These typically sit within the endocrine system, which is responsible for releasing these hormones.

Hormones are broadly split into three areas:

  • Steroid hormones – corticosteroids and sex steroids
  • Amines – these can be found in the Nervous System Report
  • Proteins and peptides

Why are our Steroid Hormones Important?

Steroid hormones are derived from cholesterol and includes testosterone, DHEA, ostrogen, progesterone and cortisol ( and their derivatives). They are then carried in the blood bound to specific carrier proteins. They are further broken down and metabolised in the liver, peripheral and target tissues. These hormones are then involved in the regulation of many physiological processes in both men and women including the reproductive system, metabolism, inflammation and the immune system.

Steroid hormone activity is influenced by both genetics, nutrition and environmental factors. This is managed by the Hypothalamus-Pituitary-Gonads/Adrenal pathway (HP-GA axis) with insufficiency or excess causing dysfunction tat directly effects how the hormones are synthesised, activated and metabolised.

Imbalances in steroid hormones can cause serious physical and mental health effects, that are detailed below.

 

What does the Genetic Hormone Test do?

The Genetic Hormone Test looks at your DNA to find tiny differences called SNPs, which can affect your body’s ability to metabolise hormones. The specific genes that this test looks at are related to the steroid hormones in addition to adrenaline, insulin and melatonin.

The Hormones test examines genes related to the regulation, synthesis, signalling, transport, and metabolism of corticosteroids and sex steroid hormones. It evaluates how genetic variants influence hormone imbalances and provides insights into the nutrients and environmental factors that can affect and improve hormone balance. This test is recommended for men and women experiencing symptoms of hormone imbalance.

The main hormones and pathways covered are split into three personalised pathways covering:

  • Steroid Hormones
  • Oestrogen Lifecycle
  • HPA and HPG Axis

This information guides strategies to address or work around any weaknesses or insufficiencies in the hormonal pathways.

 

Who would benefit most from the Genetic Hormone Test?

Imbalances in steroid hormones can cause serious physical and mental health effects. It can increase susceptibility to various health conditions including, but not an exhaustive list:

Fertility Issues

Polycystic Ovary Syndrome (PCOS),

Endometriosis

Hormonal imbalances and menstrual irregularities

Excess facial hair in females

Excess breast tissue in men Osteoporosis

Cardiovascular disease

Acne

Mood swings

Weight gain

Sexual dysfunction and low libido

Poor memory

Hormone sensitive cancers such as breast and prostate cancer

 

What is being measured in the Genetic Hormone Test

The genetic hormone test assesses the following sub-categories of genes:

Steroid Hormones: AKR1C4, CYP17A1, GABRA2, HSD11B1, SRD5A2, SULT2A1
Oestrogen: COMT, CYP1A1, CYP1B1, CYP3A4, CYP19A1, ESR1, ESR2, MTHFR, NQO1
Detoxification: ABCB1, GSTM1, GSTP1, SULT1A1, SULT1E1, UGT1A1
HPA Axis: ADRB1, ADRB2, FKBP5, MTNR1B, OPRM1, TCF7L2
HPG Axis: ESR1, ESR2, FAAH

What will I get with the Genetic Hormone Test results?

  1. Clearly illustrated and customized, color-coded genotype information .
  2. Descriptions elaborating on your gene functionality and the effects of SNP (Single Nucleotide Polymorphism).
  3. Clinically significant SNPs.
  4. Insights into nutrient and other epigenetic influences.
  5. A fully referenced report with links to research evidence.

What if I need help with the results of the Genetic Hormone Test results?

We have a team of functional medicine practitioners and registered nutritional therapists that we can refer you to help you with your results should you need any additional support. This is not included in the cost of the test.

What happens to my DNA after the Genetic Hormone Test?

Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction at 5 months and completely destroyed by 6 months.

The client report, the data and the DNA sample is never (and will never be) shared with, or sold to third parties. All of the data extraction and analysis is done in the UK.

At Smart Nutrition we pride ourselves in offering the best cost possible for the Genetic Hormone test.

 

Defects in hormonal health are wide and varied and have been associated with many clinical conditions including, but not limited to:

Fertility Issues

Polycystic Ovary Syndrome (PCOS),

Endometriosis

Hormonal imbalances and menstrual irregularities

Excess facial hair in females

Excess breast tissue in men Osteoporosis

Cardiovascular disease

Acne

Mood swings

Weight gain

Sexual dysfunction and low libido

Poor memory

Hormone sensitive cancers such as breast and prostate cancer

 

Steroid Hormones: AKR1C4, CYP17A1, GABRA2, HSD11B1, SRD5A2, SULT2A1
Oestrogen: COMT, CYP1A1, CYP1B1, CYP3A4, CYP19A1, ESR1, ESR2, MTHFR, NQO1
Detoxification: ABCB1, GSTM1, GSTP1, SULT1A1, SULT1E1, UGT1A1
HPA Axis: ADRB1, ADRB2, FKBP5, MTNR1B, OPRM1, TCF7L2
HPG Axis: ESR1, ESR2, FAAH

Buccal cheek swab.

Collecting your samples for the genetic hormone test is simple, it is a non invasive cheek swab and is suitable for all ages as long as a cheek swab can be collected.

You need to have a break from eating and drinking at least one hour before doing the genetic hormone test.

The genetic hormone test is available for anyone, including children, with the consent of a parent or guardian. When testing a child under 18, parental consent is required.

UK Orders

All UK orders for the genetic hormone test include return packaging and postage for return within the UK. The package can be put in a standard post box.
It can also be sent tracked or special delivery via a post office, the fee for this is not included.

Non UK Orders

The DNA test kit is declared as a value of £4 for customs purposes. The package may be subject to customs/ import duties, for which the recipient is liable and responsible to settle.
If kits are returned due to you not accepting fees or delivery, we are sorry but the order is not refundable.International orders return packaging is provided but it is NOT prepaid. You will need to arrange and pay for the return. For returns from Europe we recommend a tracked postal service. As samples are stable it is not necessary to choose an express service.
For Non UK orders please contact [email protected] if your country is not available at the checkout.

Results for the genetic hormone test are available in 2.5 weeks.

Your genetic hormone test results will be emailed to you.

We are here to offer ongoing support as you progress through your health journey, regardless of your test results. Should you have any inquiries or require additional assistance we are happy to help you.

Your next steps

If you feel you need additional support in addressing your health concerns, we suggest considering collaboration with the Functional Medicine and Nutrition Consultations Clinic. (website coming soon)

Renowned for their expertise, the Functional Medicine and Nutrition Consultations Clinic comprises a team of experienced nutritional therapists and certified functional medicine practitioners who excel in addressing complex health issues.Working with genetic test results needs specialised training. Chosen carefully both Olga Hamilton and Karen Preece Smith have completed their nutrigenomics training and are ready to help you.

More information about the team of qualified functional medicine and registered Nutritional therapy practitioners that are ready to help you.

Karen Preece Smith 

Methylation and Nutrition Function Medicine:
Karen has worked with nutrigenomics since 2019. She has undertaken further training with leading UK genetic lab, Lifecode Gx, to become one of their recognised Nutrigenomic practitioners. She understands Methylation genes well and can simplify their findings in relation to your CFS, digestive or hormonal issues as well as those issues which affect mental health and neurodiversity.
Olga Hamilton
Olga has been using DNA/genetics testing in her practice since 2015 to help her build personalised wellbeing and anti-ageing programmes. Genetic testing tells us how and where you are different from all other people, not just disease risks and predispositions, but also helps us tailor your diet and micronutrients. It is extremely helpful in personalising your diet and helps in prevention of genetic disorders.

As you can see Olga and Karen can help you address areas highlighted by your genetic hormone test results, crafting a personalised plan tailored to your specific needs. This comprehensive approach would include recommendations regarding your Genetic hormone test results and any necessary further diagnostic testing depending on your goals, supplementation, dietary adjustments, and lifestyle recommendations, all presented with clear, easy-to-follow guidance.

How to Book your appointment

We will send you details of how to book with the clinic along with your results.

How much will it cost.

£150 an hour but you will also receive a £20 off your first appointment discount code with the results.

How many sessions will I need to understand my genetic hormone test result

Many people book a 1 hour session to go over and understand their results.And lots of people want further ongoing support as they want to address their health concerns in more details.

Which lab do you use to process the genetic hormone test results?

We use lifecodeGX for our genetic hormone test.

 

Is the laboratory processing my genetic hormone results accredited and reputable?

Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction after 5 months and completely destroyed by 6 months.

Please see the ISO Certifications below:

  • Certification to ISO 9001 for business processes;
  • Certification to ISO 13485 for the manufacturing of substances that support health care processes and systems;
  • Accreditation to ISO 17025, for laboratory testing and calibration services;
  • Compliance with Good Laboratory Practice (GLP), Good Clinical Practice (GCP), Good Distribution Practice (GDP) and current Good Manufacturing Practice (cGMP) for pharmaceutical studies and pharmaceutical related processes;
  • Accreditation to ISO 17043 for the operation and management of proficiency testing schemes;
  • Accreditation to ISO 17034 for reference material production facilities.

Genetic Hormone Test

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PUT YOURSELF to the TEST

Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.

The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.