Test your Detoxification Genes and support any areas that are compromised.
Test your Oestrogen Genes and support any areas that are compromised.
Test your Oestrogen Genes and support any areas that are compromised.
Oestrogen is one of the two main female sex hormones that helps maintain your sexual and reproductive health, along with progesterone. Oestrogen levels fluctuate throughout the menstrual cycle and declines during menopause. The primary source of oestrogen is from the ovaries and this diminishes in menopause but it will still be produced in smaller amounts from the adrenal glands and fat tissue. Men also produce oestrogen, but are significantly lower levels, and this is important for producing sperm and libido.
There are three major types of oestrogen:
Oestrone (E1) – Primary oestrogen that your body makes post menopause
Oestradiol (E2) – Primary form of oestrogen during the reproductive years and is the most potent.
Oestriol (E3) – Primarily produced during pregnancy and the weakest form.
Oestrogen moves around the body and will attach to areas where there are oestrogen receptors and these are broken down into two categories:
ER alpha – increases the action of oestrogen
ER beta – decreases the action of oestrogen
Oestrogen main role is around growth and production of cells that are involved on the female reproductive cycle. Working with progesterone, oestrogen makes the development of secondary sex characteristics along with menstruation, pregnancy and menopause possible. During puberty, oestrogen levels rise that is needed for the development of secondary sex characteristics such as breasts and hips but also changing overall body composition. During menstruation, oestrogen is involved in ovulation and the thickening of the uterus lining, along with progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Oestrogen peaks before ovulation and thus reduces cervical mucus, making it easier to become pregnant.
It also has many functions outside of reproduction and is involved in cholesterol levels, bone density and muscle mass, blood sugar balance, anti-inflammatory, circulation and blood flow, brain function and collagen production.
The Genetic Oestrogen Test looks at your DNA to find tiny differences called SNPs, which can affect the balance of oestrogen in the body.
This test examines the genes involved in the oestrogen lifecycle. It assesses how gene variants impact the production, activation, and elimination of oestrogens. In addition, it provides details on how nutrients and environmental factors can influence oestrogen and their overall balance. The genetic oestrogen test is particularly recommended for women who suspect they have an oestrogen related conditions (detailed further below).
The report then provides personalised recommendations based on the above and how to support nutritionally to alleviate symptoms.
Oestrogen imbalance underlies many health conditions, especially female health. Some of the most common are listed below:
Endometriosis
Infertility
Obesity
Breast or uterine cancer
Female sexual dysfunction (FSD)
Fibrocystic breast
Osteoporosis
Polycystic ovary syndrome (PCOS)
Primary ovarian insufficiency
Premenstrual syndrome
Uterine fibroids
Vaginal atrophy
Anorexia
Although most of the above are linked with females there are some symptoms for men:
Low sex drive
Erectile dysfunction and infertility
Gynecomastia – enlarged breasts in males
The genetic oestrogen balance report can look at genetic imbalances in these oestrogen pathways so that they can be supported.
The genetic Oestrogen Test assesses genes associated with five sub-cycles:
Synthesis: CYP17A1, CYP19A1 and SULT2A1
Activation: CYP1A1, CYP1B1 and CYP3A4
Receptors: ESR1 and ESR2
Methylation: COMT and MTHFR
Metabolism: GSTM1, GSTP1, SULT1A1, SULT1E1 and UGT1A1
We have a team of functional medicine practitioners and registered nutritional therapists that we can refer you to help you with your results should you need any additional support. This is not included in the cost of the test.
Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction at 5 months and completely destroyed by 6 months.
The client report, the data and the DNA sample is never (and will never be) shared with, or sold to third parties. All of the data extraction and analysis is done in the UK.
At Smart Nutrition we pride ourselves in offering the best cost possible for the Genetic Oestrogen test.
Oestrogen imbalance underlies many health conditions, especially female health. Some of the most common are listed below:
Endometriosis
Infertility
Obesity
Breast or uterine cancer
Female sexual dysfunction (FSD)
Fibrocystic breast
Osteoporosis
Polycystic ovary syndrome (PCOS)
Primary ovarian insufficiency
Premenstrual syndrome
Uterine fibroids
Vaginal atrophy
Anorexia
Although most of the above are linked with females there are some symptoms for men:
Low sex drive
Erectile dysfunction and infertility
Gynecomastia – enlarged breasts in males
The genetic Oestrogen Test assesses genes associated with five sub-cycles:
Synthesis: CYP17A1, CYP19A1 and SULT2A1
Activation: CYP1A1, CYP1B1 and CYP3A4
Receptors: ESR1 and ESR2
Methylation: COMT and MTHFR
Metabolism: GSTM1, GSTP1, SULT1A1, SULT1E1 and UGT1A1
Buccal cheek swab.
Collecting your samples for the genetic oestrogen test is simple, it is a non invasive cheek swab and is suitable for all ages as long as a cheek swab can be collected.
You need to have a break from eating and drinking at least one hour before doing the genetic oestrogen test.
As the test is looking at genetic code, which is fixed, the test is not impacted by illness, infections, medication, the food you eat, or supplements you take. To avoid contamination of the sample, please abstain from eating/drinking for at least 1 hour before testing.
The genetic oestrogen test is available for anyone, including children, with the consent of a parent or guardian. When testing a child under 18, parental consent is required.
The turnaround time for genetic testing varies between 2.5 and 3.5 week. Most results are back in 2.5 weeks. However the laboratory runs samples in batches which occasionally means results take up to 3.5 weeks.
Your genetic oestrogen test results will be emailed to you.
We are here to offer ongoing support as you progress through your health journey, regardless of your test results. Should you have any inquiries or require additional assistance we are happy to help you.
If you feel you need additional support in addressing your health concerns, we suggest considering collaboration with the Functional Medicine and Nutrition Consultations Clinic. (website coming soon)
Karen Preece SmithÂ
As you can see Olga and Karen can help you address areas highlighted by your genetic oestrogen test results, crafting a personalised plan tailored to your specific needs. This comprehensive approach would include recommendations regarding your Genetic oestrogen test results and any necessary further diagnostic testing depending on your goals, supplementation, dietary adjustments, and lifestyle recommendations, all presented with clear, easy-to-follow guidance.
How to Book your appointment
£150 an hour but you will also receive a £20 off your first appointment discount code with the results.
Many people book a 1 hour session to go over and understand their results. Lots of people want further ongoing support as they want to address their health concerns in more details.
We use lifecodeGX for our genetic oestrogen test.
Each test is processed in an ISO certified UK laboratory and all samples are completely destroyed after 3 months. All client genotyping data is marked for destruction after 5 months and completely destroyed by 6 months.
Please see the ISO Certifications below:
LifeCodeGX does not provide the raw data. It is only used as a means to produce the report and therefore not produced in the report.
If you did your genetic test within 3 months we can upgrade it without you needing a new DNA kit.
We don’t use data from any third parties like 23&Me. Unfortunately, it doesn’t include many of the important SNPs that are needed to perform our analysis and produce our detailed reports. We also prefer to use our own testing and data for confidentiality reasons. All of our packages include a Lifecode Gx DNA test to ensure completeness and accuracy.
All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients is completely incidental.Â
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£265.00
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£196.00
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Please do not return samples to the laboratories that may arrive after Wednesday 27th March and up to and including Monday 2nd April.
The laboratories are closed from the 28th March – 2nd April for the Easter Holiday.